Tissue Engineering: Building Organs from Scratch

Katu Amina H.

School of Natural and Applied Sciences Kampala International Uganda

ABSTRACT

Tissue engineering has emerged as a transformative interdisciplinary field aimed at addressing organ shortages and advancing regenerative medicine. By integrating biology, materials science, and engineering, researchers have developed biomaterials, scaffolds, and advanced cell culture techniques to create functional tissue constructs. Natural and synthetic biomaterials play a pivotal role in creating scaffolds that mimic native extracellular matrices, facilitating cell adhesion and differentiation. Stem cells, bioprinting technologies, and organ-on-a-chip systems are expanding possibilities for clinical applications, including cartilage repair, liver regeneration, and artificial organ development. However, the field faces technical challenges, including immune rejection, long-term viability, and ethical considerations surrounding stem cell use. Despite these obstacles, the integration of robotics, artificial intelligence, and personalized medicine promises to revolutionize healthcare by reducing costs and enhancing treatment outcomes. This review highlights key developments, challenges, and future directions in tissue engineering, emphasizing its potential to transform the landscape of medicine.

Keywords: Tissue engineering, Biomaterials, Scaffolds, Stem cells, Regenerative medicine, 3D bioprinting.

CITE AS: Katu Amina H.. (2025). Tissue Engineering: Building Organs from Scratch. Research Output Journal of Biological and Applied Science 5(1):15-18. https://doi.org/10.59298/ROJBAS/2025/511518