The Role of Medicinal Plants in Supporting Gut Health in Diabetic Patients

Nalongo Bina K.

Faculty of Medicine Kampala International University Uganda

ABSTRACT

Type 2 diabetes mellitus (T2DM), a metabolic disorder marked by insulin resistance and progressive β-cell dysfunction, is on the rise globally and is often accompanied by chronic complications. Recent scientific interest has shifted toward the gut microbiota’s role in the development and management of T2DM. Dysbiosis an imbalance in gut microbial communities has been strongly linked to impaired gut barrier function, systemic inflammation, and metabolic dysfunctions that exacerbate hyperglycemia. Medicinal plants, especially those used in traditional systems like Chinese herbal medicine, present a promising avenue for restoring gut homeostasis and modulating metabolic pathways. This paper explores the potential of bioactive components in medicinal plants, such as polysaccharides, flavonoids, and saponins, to regulate gut microbiota and support glycemic control. Focusing on Astragalus membranaceus and other synergistic herbs, we analyze the mechanisms by which these natural compounds enhance intestinal integrity, reduce inflammation, and stimulate beneficial microbial growth. Understanding the gut–diabetes axis and identifying efficacious plant-based interventions may revolutionize integrative and preventive approaches to diabetes care.

Keywords: Type 2 Diabetes Mellitus (T2DM), Gut Microbiota, Medicinal Plants, Astragalus membranaceus, Dysbiosis, Phytochemicals, Insulin Resistance, Traditional Chinese Medicine.

CITE AS: Nalongo Bina K. (2025). The Role of Medicinal Plants in Supporting Gut Health in Diabetic Patients Research Output Journal of Biological and Applied Science 5(3):133-139. https://doi.org/10.59298/ROJBAS/2025/53133139