Theranostic Nanoplatforms for Obesity-Associated Diabetes: Combining Imaging and Therapy

Nalongo Bina K.

Faculty of Medicine Kampala International University Uganda

                                                                                    ABSTRACT
Obesity-associated diabetes (OAD), particularly type 2 diabetes (T2D), is a complex metabolic disorder characterized by insulin resistance, chronic inflammation, and dysregulated lipid metabolism. Early detection and personalized treatment strategies are crucial for effective management and prevention of complications. Theranostic nanoplatforms, which combine both therapeutic and diagnostic functions, offer a promising approach for managing OAD by enabling early diagnosis, monitoring disease progression, and delivering targeted therapies. These platforms integrate imaging agents for real-time monitoring with therapeutic agents aimed at modulating metabolic pathways. This review explores the role of theranostic nanoplatforms in the management of obesity-associated diabetes, focusing on their design, mechanisms of action, and applications in
diagnosis and treatment. Challenges related to biocompatibility, targeting specificity, and clinical translation are also discussed, alongside future perspectives for advancing these nanoplatforms in clinical practice.

Keywords: theranostic nanoplatforms, obesity-associated diabetes, type 2 diabetes, imaging, therapy, insulin
resistance.

CITE AS: Nalongo Bina K. (2026). Theranostic Nanoplatforms for Obesity-Associated Diabetes: Combining Imaging and Therapy. Research Output Journal of Biological and Applied Science 6(1):69-76. https://doi.org/10.59298/ROJBAS/2026/616976